Effects of dimethyl 2, 2-dichlorovinyl phosphate on the sodium, potassium and calcium content in the kidney and liver of Clarias gariepinus
Abstract
Dimethyl 2, 2-dichlorovinyl phosphate is an organophosphorus insecticide used in the control of several plant and animal pests. This study evaluated the effects of dimethyl 2, 2-dichlorovinyl phosphate on the electrolytes (calcium, sodium and potassium) in the kidney and liver of Clarias gariepinus. The fish samples were purchased from private farm in Aluu Port Harcourt, Nigeria. The fishes were carefully housed to prevent contamination and three different concentrations of the toxicant were prepared i.e. 0.00ppm, 0.10ppm and 0.20ppm. At the end of the experiment (four days), the fishes were dissected and the internal organs i.e. liver and kidney were collected and 0.5g of each macerated, and a few drop of physiological saline added before centrifuging at 3000 rpm for 10 minutes. The calcium, sodium and potassium content were analyzed using standard methods. Results showed that calcium, potassium and sodium ranged from 0.80 – 1.40mg/l, 3.80 – 7.10mg/l and 10.20 – 16.40mg/l respectively (Kidney) and 1.00 – 1.13mg/l, 10.60 – 17.73mg/l and 6.80 – 12.80 mg/l respectively (liver). With the exception of calcium there was significant variations (P<0.05) among the various concentrations of sodium and potassium. The study confirms that dimethyl 2, 2-dichlorovinyl phosphate can alter the electrolytes balance of Clarias gariepinus.Downloads
References
Seiyaboh, E.I. Inyang, I.R., Gijo, A.H. and Adobeni, G.D. Acute Toxicity of Paraquat Dichloride on Blood Plasma Indices of Clarias gariepinus. IOSR Journal of Environmental Science, Toxicology and Food Technology, 2013; 7(6): 15 – 17.
Lawson, E.O., Ndimele, P.E., Jimoh A.A. and Whenu, O.O. Acute Toxicity of Lindane (Gamma Hexachloro-Cyclohexane) to African Catfish (Clarias gariepinus, Burchell, 1822). International Journal of Animal and Veterinary Advances, 2011; 3(2): 63-68.
Akan, J.C., Mohammed, Z., Jafiya L. and Ogugbuaja VO. Organochlorine Pesticide Residues in Fish Samples from Alau Dam, Borno State, North Eastern Nigeria. J Environ Anal Toxicol., 2013; 3: 171. doi:10.4172/2161-0525.1000171.
Ezemonye, L. and Ogbomida, T.E. Histopathological Effects of Gammalin 20 on African Catfish (Clarias gariepinus). Applied and Environmental Soil Science, 2010: http://dx.doi.org/10.1155/2010/138019.
Wilson C. and Tisdell C. The economics, ecology and the environment. Why farmers continue to use pesticides despite environmental, health and sustainability costs. Working Paper No. 53. 2000.
Ogamba, E.N., Inyang, I.R. and Okechukwu, O.C. Effect of kartodin 315 EC(Dimethoate) and Lambda-Cyalothrin on electrolytes of Clarias gariepinus. Journal of Environmental Sciences, Toxicology and Food Technology, 2013; 5(2): 1 – 4.
Li, Q, Nakadai A, Takeda K. and Kawada, T. Dimethyl 2,2-dichlorovinyl phosphate (DDVP) markedly inhibits activities of natural killer cells, cytotoxic T lymphocytes and lymphokine-activated killer cells via the Fas-ligand/Fas pathway in perforin-knockout (PKO) mice. Toxicology, 2004; 204(1):41-50.
Srivastava, S., Kumari, U., Rai, A.K., Mittal, S. and Mittal, A.K. Alterations in the Gill Filaments and Secondary Lamellae of Cirrhinus mrigala Exposed to “Nuvan,†an Organophosphorus Insecticide. Journal of Histology, 2014: http://dx.doi.org/10.1155/2014/190139.
Ajani, F., Ajiboye, A.O. and Oyelowo, O.O. Effects of Oxadiazon on Nutrient Utilization and Growth of African Catfish (Clarias gariepinus). American Journal of Agricultural Science, 2015; 2(3):121-125.
http://www.fao.org/docrep/x5042e/x5042e0f.htm
Wikipedia. Dichlorvos. 2015. https://en.wikipedia.org/wiki/Dichlorvos. Accessed 30 June, 2015.
Mekkawy, IA.A., Mahmoud, U.M. and Mohammed, R.H. Protective effects of tomato paste and Vitamin E on Atrazine-Induced Hematological and biochemical characteristics of Clarias gariepinus (Burchell,1822). Global Advanced Research Journal of Environmental Science and Toxicology, 2013; 2(1): 011-021.
Dahunsi, S.O., Oranusi, S.U and Ishola, R.O. Biochemical profile of Clarias gariepinus exposed to sub-lethal concentrations of chemical additives effluent. International Journal of Research in Environmental Science and Technology, 2011; 1 (4): 52-58.
Oyedapo, F., Akinduyite, I. Acute Toxicity of Aqueous Morinda lucida leaf extracts to Nile Tilapia, Oreochromis niloticus (Linnaeus 1857). Proceedings of the Ninth International Symposium on Tilapia in Aquaculture. Shanghai, China. April 22nd-24th, 2011. 52-59.
Murthy, K.S., Kiran, B.R. and Venkateshwarlu, M. A review on toxicity of pesticides in Fish. International Journal of Open Scientific Research, 2013; 1(1): 15-36.
Ladipo M. K., Doherty V. F., Oyebadejo S. A. Acute Toxicity, Behavioural Changes and Histopathological Effect of Paraquat Dichloride on Tissues of Catfish (Clarias Gariepinus). International Journal of Biology, 2011; 3(2): 67 – 74.
Okechukwu, E.O. and Auta, J. The Effects of Sub-lethal Doses of Lambda-cyhalothrin on Some Biochemical Characteristics of the African Catfish Clarias gariepinus . Journal of Biological Sciences, 2007; 7: 1473-1477.
Udroiu, I. The micronucleus test for aquatic toxicology. In: Aquatic Toxicology Research Focus Svensson E.P. (Editor). Nova Science Publishers, Inc. pp. 1- 16, 2007.
Izah SC, and Angaye TCN. Ecological perception of fish farmers in Yenagoa Metropolis, Nigeria. Bulletin of Advanced Scientific Research, 2015; 1(1): 26 – 28.
Ineyougha ER,Orutugu LA, Izah SC. Assessment of microbial quality of smoked Trachurus trachurus sold in some markets of three South-south States, Nigeria. International Journal of Food Research, 2015; (2): 16 – 23.
Ogamba, E.N., Izah, S.C., Ebiowe, R.G. Bioconcentration of Mercury, Lead and Cadmium in the bones and muscles of Citharinus citharaus and Synodontis clarias from the Amassoma Axis of River Nun, Niger Delta, Nigeria. Research Journal of Pharmacology and Toxicology, 2015; 1(1): in press.
Wokoma, O.A.F. Heavy Metal Concentrations in Three Commercially Important Fish Species in the Lower Sombreiro River, Niger Delta, Nigeria. Journal of Natural Sciences Research, 2014; 4(22): 164 –168.
Akinsorotan A.M. Toxicity of dizensate (Glyphosate herbicide) on Clarias gariepinus fingerlings. Advanced Research in Biological Sciences, 2014; 2(1):1-5.
Napit, M.K. The effect of pesticides on fish fauna of Bhopal lower lake (M.P.). African Journal of Environmental Science and Technology, 2013; 7(7):725-727.
Ogamba, E.N., Inyang, I.R. and Azuma, I.K. Effect of Paraquat Dichloride on Some Metabolic and Enzyme Parameters of Clarias gariepinus. Current Research Journal of Biological Sciences, 2011; 3(3): 186-190.
Abolagba, O.J., Igene, J.O. and Usifoh, C.O. Studies of Pesticide Residues in Smoked Catfish (Clarias Gariepinus) in Nigeria: Some Health Implications. Australian Journal of Basic and Applied Sciences, 2011; 5(5): 496-502.
Kori-Siakpere, O. and Oboh, E. C. Haematological effects of sublethal concentrations of tobacco leaf dust on the African catfish: Clarias gariepinus (Burchell 1822). Archives of Applied Science Research, 2011; 3 (2):493-502
Olatunde, A.A.Length weight relationship and diet of Clarias lazera (C&V) in Zaria, Nigeria. Proceedings of the 3rd annual conference of the fisheries society of Nigeria (FISON), Maiduguri. 22nd – 25th Feb, 1983, 59 - 62.
Grinshaw, G. Chemistry. Ibadan. Evans Brother Ltd., 1978.
Inyang, I.R., Daka, E.R. and Ogamba, E.N. Changes in electrolyte activities of Clarias gariepinus exposed to diazinon. Bio. Environ. Sci. J. Trop., 2010; 7: 198- 200.
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