Research Journal of Pharmacology and Toxicology <p>Research Journal of Pharmacology and Toxicology (RJPT) in&nbsp;monthly&nbsp;online peer reviewed &nbsp;journal of Pharmacology and toxicology.</p> ASD Publisher en-US Research Journal of Pharmacology and Toxicology <p>Authors who publish with this journal agree to the following terms:</p> <p>A) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a&nbsp;<a href="" target="_new">Creative Commons Attribution License</a>&nbsp;that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</p> <p>B) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</p> <p>C) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See&nbsp;<a href="" target="_new">The Effect of Open Access</a>).</p> <p>D) Author agree to submit <a href="/download/Copyrightform_ASD.docx" target="_blank">Copyright form</a> after accepetance of article.</p> The effect of erythropoietin on ovarian epithelium edema during ischemia reperfusion injury in rats <p><strong>Object:</strong> This experiment investigated a probable recessing effect of erythropoietin (Epo) in a rat model of ovarian ischemia-reperfusion (IR) injury concerning the mean ovarian epithelium edema (OE) lesions.</p> <p><strong>Methods:</strong> 40 rats of mean weight 247.7 g were used totally. The OE lesions scores were evaluated at 60 min (groups A and C) and at 120 min (groups B and D) of reperfusion; after Epo administration in groups C and D.</p> <p><strong>Results:</strong> Epo administration non-significantly decreased the OE scores by 0.3 without lesions [-0.8356043 - 0.2356043] (p= 0.2803). Reperfusion time kept non-significantly increased the OE by 0.35 without lesions [-0.2356043 - 0.8356043] (p=0.2557). However, erythropoietin administration and reperfusion time together non-significantly decreased the OE scores by 0.1272727 without lesions [-0.4530022 - 0.1984567] (p=0.4339).</p> <p><strong>Conclusion:</strong> Epo administration showed a non-significant short-term recessing trend for OE scores without lesions alteration. Perhaps, a longer study time than 2 hours or a higher Epo dosage may reveal clearer and significant effects.&nbsp;&nbsp;</p> Constantinos Tsompos C. Panoulis K Τοutouzas A. Triantafyllou G. Ζografos A. Papalois ##submission.copyrightStatement## 2017-05-11 2017-05-11 2 3 08 11