Biomolluscicidal Activities of Some Solvent Extracts of Jatropha Curcas Leaves against Vectors of Schistosomiasis
Abstract
Jatropha curcas has emerged as a mantra amongst bioactive therapeutic plants due to it multipurpose application, bioavalability and especially certain envisaged metabolites. Notwithstanding, some problems envisaged with chemotherapeutic intervention of schistosomiasis includes; ecotoxicity, mobidity abatement and vector proliferation. The biomolluscicidal Activities of solvent extracts (chloroform, ethanol, ethyl acetate and n-hexane) of the Leaves of J. curcas against Bulinus globosus and B. rholfsi in a 24-h static non-renewal test was assessed. Results indicated varying degrees of mortalities, the chloroform, ethanol, ethyl acetate and n-hexane extracts against B. globosus had LC50 values of 25.00, 18.75, 41.63 and 37.40ppm respectively. Comparatively, the solvent extracts against B. rholfsi demonstrated a slightly higher LC50 values of 31.25, 25.00, 50.00 and 38.70ppm for chloroform, ethanol ethyl acetate and n-hexane extracts respectively. While, the positive control induced mortality at 1ppm in less than 24h, the snails survived the negative control within the same period. These results showed that the above named solvent leaf extracts of J. curcas can be applied in the integrated management of schistosomiasis.
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