Patented Pharmaceutical Reconstitutable Sustained Release Suspension

  • Sahilhusen I. Jethara Research Scholar, Gujarat Technological University, Gujarat Shri B. M. Shah College of Pharmaceutical Education & Research, Modasa-383315, Gujarat
  • Mukesh R. Patel Shri B. M. Shah College of Pharmaceutical Education & Research, Modasa-383315, Gujarat,
  • Alpesh D. Patel Shri B. M. Shah College of Pharmaceutical Education & Research, Modasa-383315, Gujarat,
Keywords: Reconstitutable suspension, Patents, Sustained Release (SR), Microencapsule, Drug delivey

Abstract

At the present time reconstitutable suspensions are obtainable in a market. Oral liquor suspensions are majorly designed for the patients with difficulty in swallowing. Reconstitutable suspensions necessitate water to prior for mixing. Sustained release (SR) suspensions aimed at controlling the rate of release by maintaining desire drug levels in the blood for long duration of time. An oral suspension could be the most excellent fitting dosage form intended for geriatric and pediatric patients. They comprise improvement of the rate and extent of drug absorption, higher patient compliance, reduction of side effects and taste masking of bitter drug.Reconstitutable SR suspensions are prepared by numerous novel approaches to design and development of variety of drugs. They are prepared by using a variety of polymer like Cellulose acetate, EC, HPMC phthalate, Eudragit, Xanthan gum etc. for enteric coating purpose, which are give controlled drug delivery from the granules. SR suspension developed into the research characterized by Scanning electron microscopy (SEM), particle size analysis, drug entrapment efficiency, and In-vitro Drug Release. SR suspension will be benefited to avoid fluctuations in blood drug plasma concentration and gives its action for an entire period of time.

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Published
2015-06-09
Section
Review Articles