Emerging evidence on the role of secondary metabolites as nutraceutical

  • Manas Kumar Das Department of Pharmacy, IEC-CET, Greater Noida, U.P.
  • Saumya Das Department of Pharmaceutical Technology, Noida Institute of Engineering and Technology, Greater Noida, Uttar Pradesh
Keywords: Nutraceuticals, Pharmaceutical, Pharmacological

Abstract

Nutraceuticals have time-honored considerable interest because of their reputed safety, nutritional and therapeutic potential effects. Pharmaceutical and nutritional industries are conscious of the monetary success taking advantage of the more health-seeking consumers. Natural products such as cereals are likely to form the basis of nutraceutical as its revolution represents an enormous opportunity for growth and expansion. Wheat, rice, millets, barley, oat, buckwheat, corn, sorghum, flaxseed psyllium, brown rice, and products are notify the most common cereal based functional foods and nutraceuticals. The nutrients in the cereals have identified prospective for reducing the risk of coronary heart disease, diabetes, tumor incidence, cancer risk, blood pressure, reduces the rate of cholesterol and fat absorption, delaying gastrointestinal emptying and providing gastrointestinal health. Thus, the regular insertion of cereals and their processed products can make a payment to health endorsement and disease avoidance.

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References

Rajasekaran A, Sivagnanam G, Xavier R, Nutraceutical as therapeutic agents, Research J. Pharm. And Tech., 2008, 1(4), 328-340.

Kramer K, Hoppe PP, Packer L, Nutraceuticals in health and disease prevention, New York: Marcel Dekker Inc., 2001, 1-26.

Andlauer W, Furst P, Nutraceuticals: a piece of history, present status and outlook, Food Research International, 2002, 35, 171-176.

Whitman M, Understanding the perceived need for complementaryand alternative nutraceuticals: lifestyle issues, Clin J Oncol Nurs., 2001, (5),190-194.

Bagchi D, Nutraceuticals and functional foods regulations in the United States and around the world, Toxicol., 2006, 221,1- 3.

Halsted CH, Dietary supplements and functional foods: 2 sides of a coin? Am J Clin Nutr; 2003, 77, 1001S-1007S.

Taylor CL, Regulatory frameworks for functional foods and dietary supplements, Nutr Rev., 2008, (62) 55-59.

Kroes R, Walker R, Safety issues of botanicals and botanical preparations in functional foods, Toxicol., 2004,(198),213-220.

Roy C, Rink, Khanna S, Body weight and abdominal fat gene expression profile in response to a novel hydroxycitric acid based dietary supplement, Gene Exp., 2004, (11), 251-262.

Singh KK, Ethnomedicinal plants diversity in Sonbhadra district of southern Uttar Pradesh, India-utilization and conservation. Proceeding of the Ethnobiology in human welfare: Abstracts of the 4th International Congress of Ethnobiology. Centre, 2004, 159-174.

Siddique NA, Bari MA, Naderuzzaman ATM, Khatun N, Rahman MH, Collection of indigenous knowledge and identification of endangered medicinal plants by questionnaire survey in Barind Tract of Bangladesh, J. Biological Sci., 2004, 4, 72- 80.

Schiller RN, Barranger E, Schauss AG, Nichols E, Life style management of Obesity, JAMA., 2001, (4), 34-41.

Bell SJ, Goodrick GK, A Functional Food Product for the Management of Weight, Critical Reviews in Food Science and Nutrition., 2002, (42),163-178.

Woodgate DE, Conquer JA, Prevalence of self-treatment with complementary products and therapies for weight loss: A randomized, cross sectional Study in Overweight and Obese Patients in Colombia, Current Therapeutic Research., 2003, (64), 248-262.

Kasbia GS, Functional foods and nutraceuticals in the management of obesity, Nutrition and Food Science., 2005, (35), 344-351.

Expert Committee on the Diagnosis and Classification of Diabetes Mellitus Diabetes Care. Alexandria, Virginia, USA, 2003, 23-25.

Wild S, Thomasset SC, Berry DP, Garcea G, Marczylo T, Steward WP, Gescher AJ, Dietary polyphenolic phytochemicals - Promising cancer chemopreventive, Int J Cancer., 2007, (120), 451-464.

Messina MJ, Emerging evidence on the role of soy in reducing prostate cancer risk, Nutr Rev., 2003, (61), 117-131.

Dijsselbloem N, Vanden Berghe W, De Naeyer A Haegeman G. Soy isoflavone phyto-pharmaceuticals in interleukin-6 affections, Biochem Pharmacol., 2004, (68), 1171-1185.

Rao AV, Rao LG, Pharmacological Research., 2007, (55), 207-212.

Kucuk O, Sarkar FH, Sakr W, Khachik F, Djuric Z, Banerjee M, Pollak MN, Bertram JS and Wood DP, Lycopene in the Treatment of Prostate Cancer, Pure Appl Chem., 2002, (74), 1443-1450.

Stahl W, Sies H, Bioactivity and Protective Effects of Natural Carotenoids. Biochimica Biophysica Acta (BBA) - Molecular Basis of Disease., 2005, 1740, 101-107.

Miller EC, Hadley EW, Schwartz SJ, Erdman JW, Boileau TWM, Clinton SK, Lycopene, tomato products, and prostate cancer prevention. Have we established causality? Pure Appl. Chem., 2002, (74), 1435-1441.

McMillan DC, Talwar D, Sattar N, Underwood M, O'reilly DSJ, Mcardle C, The relationship between reduced vitamin antioxidant concentrations and the systemic inflammatory response in patients with common solid tumours, Clinical Nutrition., 2002, (2), 161-164.

Sandoval M, Zhang XJ, Condezo LA, Lao J, Angeles FM, Musah RA, Bobrowski P, Miller MJS, Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are independent of their alkaloid content, Phytomedicine, 2002, (9), 325-337.

Hardin S R, Cat's claw: an Amazonian vine decreases inflammation in osteoarthritis, Complementary Therapies in Clinical Practice., 2007, (13), 25-28.

Lyons MM, Yu C, Toma RB, Cho SY, Reiboldt W, Lee J, Breemen RB, Resveratrol in raw and baked blueberries and bilberries, J Agric Food Chem., 2003, (51), 5867-5870.

Jang M, Cai L, Udeani GO, Cancer chemopreventive activity of resveratrol, a natural product derived from grape, Science., 1997, 275, 218-229.

Balch SA, Mckenney CB, Auld D, Evaluation of gamma-linolenic acid composition of evening primrose (Oenothera) species native to Texas, Hort Science., 2003, (38), 595-598.

Kapoor R, Huang YS, Gamma linolenic acid: an antiinflammatory omega-6 fatty acid, Cur Parm Biotechnol., 2006, (7), 531-534.

Clark K, Nutritional considerations in joint health, Clin Sports Med., 2007, (26), 101-118.

Chan PS, Caron JP, Rosa GJM, Glucosamine and chondroitin sulfate regulate gene expression Osteoarthritis and Cartilage., 2005, (13), 387-394.

Alarcon de la Lastra C, Martin MJ, Motilve V, Antiulcer and gastroprotective effects of quercetin, Pharmacol., 1994, (48), 56-62.

Formica JV, Regelson W, Review of the Biology of Quercetin and Related Bioflavonoids, Food and Chemical Toxicology., 1995, (33), 1061-1080.

Seddon J, Multivitamin-multimineral supplements and eye disease: age-related macular degeneration and cataract Nu, M Am J Clin tr., 2007, (85), 304S-307S.

Rice-Evans C, Flavonoid antioxidants, Curr Med Chem., 2001, (8), 797-807.

Kalioraa AC, Dedoussisa GVZ, Schmidtb H, Dietary antioxidants in preventing atherogenesis, Atherosclerosis., 2006, (187), 1-17.

Murthy KN, Vanitha A, Rajesha J, Swamy M, Sowmya PR, Ravishankar GA, In vivo antioxidant activity of carotenoids from Dunaliella salina - a green microalga, Life Sci., 2005, (76), 1381-1390.

Kruger CL, Murphy M, DeFreitas Z, Pfannkuch F, Heimbach J, An innovative approach to the determination of safety for a dietary ingredient derived from a new source: case study using a crystalline lutein product, Food Chem Toxicol., 2002, (40), 1535-1549.

Alzheimer A, An unusual illness of the cerebral cortex, Allgemeine Zeitschr Psychisch- Gerichtliche Medizin., 1907, (64), 146-148.

Geldmacher DS, Whitehouse P, Differential diagnosis of Alzheimer's disease. J Neurolog., 1997, (48), 2-9.

Canadian Study of Health and Aging Working Group. Study methods and prevalence of dementia, Can Med Assoc J., 1994, (150), 899-913.

Cui K, Luo Xu K, Ven Murthy M, Role of oxidative Stress in neurodegeneration: recent developments in assay methods for oxidative stress and nutraceutical antioxidants, Progress in Neuro-Psychopharmacology and Biologica Psychiatry., 2004, (28), 771-799.

Fishere O, Naughton DP, Why nutraceuticals do not prevent or treat Alzheimer’s disease, Nutrition Journal., 2005, (4), 14.

Devising RC, Parkinson's Disease: A Guide For Patient and Family, New York: Raven Press., 1978, 149.

Etminan M, Gill SS, Samii A, Intake of vitamin E, vitamin C and carotenoids and the risk of Parkinson's disease: a meta analysis, Lancet Neurol., 2005, (4), 362.

The Ninds Net-Pd Investigators. A randomized, double blind, futility clinical trial of creatine and minocycline in mearly Parkinson disease, Neurology., 2006, (66), 664-671.

Glenville M, Nutritional supplements in pregnancy: commercial push or evidence based, Curr Opin Obstet Gynecol, 2006, (18), 642-647.

Haider BA, Bhutta ZA, Multiple-micronutrient supplementation for women during pregnancy, Cochrane Database Syst Rev., 2006, (18), 905.

Losso JN, Targeting excessive angiogenesis with functional foods and nutraceuticals, Food Science Trends in and Technology., 2003, (14), 455-468.

Latif S, Anwar F, Ashraf M , Gilani AH, Moringa oleifera: a food plant with multiple medicinal uses, 2007, (21), 708-711.

Published
2015-06-09
Section
Review Articles