Cadmium Induced Toxicity
Abstract
Cadmium is a highly toxic metal that can disrupt a number of biological systems. The cadmium is responsible for the generation of reactive oxygen species, glutathione depletion, lipid peroxidation, proteins cross-liking, and DNA damage; ultimately result in oxidant induced cell death. Cadmium stimulates and binds to various biological components such as proteins and non-protein sulfhydryl groups, macromolecules and metallothionein. Cadmium intoxication can lead to kidney, bone, and pulmonary damage, damage to the lungs, liver, and kidneys in animals and humans in cadmium-exposed conditions.This review gives detail about mechanism and diseases resulting from cadmium induced toxicity.
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