Cadmium Induced Toxicity

  • Blessy B. Mathew Department of Biotechnology, Sapthagiri College of Engineering, Bangalore- 57, Karnataka,
  • Gagana V. Department of Biotechnology, Sapthagiri College of Engineering, Bangalore- 560057
Keywords: Cadmium toxicity, carcinogenesis, cardiovascular dysfunction, hepatotoxicity, neurotoxicity, nephrotoxicity, bone demineralization

Abstract

Cadmium is a highly toxic metal that can disrupt a number of biological systems. The cadmium is responsible for the generation of reactive oxygen species, glutathione depletion, lipid peroxidation, proteins cross-liking, and DNA damage; ultimately result in oxidant induced cell death. Cadmium stimulates and binds to various biological components such as proteins and non-protein sulfhydryl groups, macromolecules and metallothionein. Cadmium intoxication can lead to kidney, bone, and pulmonary damage, damage to the lungs, liver, and kidneys in animals and humans in cadmium-exposed conditions.This review gives detail about mechanism and diseases resulting from cadmium induced toxicity.

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Published
2015-02-28
How to Cite
1.
Mathew B, V. G. Cadmium Induced Toxicity. AMS [Internet]. 28Feb.2015 [cited 21Feb.2020];2(2):47-0. Available from: http://asdpub.com/index.php/ams/article/view/91
Section
Review Articles

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