Various pyrrole and pyrrolidine derivatives acts as new trends in development of antimycobacterial agents

  • Mohammad Asif Department of Pharmacy, GRD (PG) Institute of Management & Technology, 248009, Dehradun, (Uttarakhand)
Keywords: Pyrrole derivatives, Anti-tubercular activity, MDR-TB

Abstract

Pyrrole and pyrrolidine derivatives are important antimicrobial agents. Some pyrrole and pyrrolidine derivatives are under investigation for the treatment of tuberculosis and multidrug-resistant tuberculosis. In this article, study the pyrrole and pyrrolidine derivatives with anti-mycobacterial properties, mode of action and structure activity relationship studies of the pyrrole derivatives. Furthermore, we update the synthesis and activity of pyrrole and pyrrolidine derivatives as a new class of potent anti-mycobacterial agents. Furthermore, particularly interesting is their activity against MDR-TB.

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Published
2015-02-28
How to Cite
1.
Asif M. Various pyrrole and pyrrolidine derivatives acts as new trends in development of antimycobacterial agents. AMS [Internet]. 28Feb.2015 [cited 21Feb.2020];2(2):42-6. Available from: http://asdpub.com/index.php/ams/article/view/70
Section
Review Articles

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