Membrane depolarization in stroke patients

  • Nnodim Johnkennedy Department of Medical Laboratory Sciences, Faculty of Health Sciences, Imo State University Owerri
  • Nwobodo Emmanuel Department of Biochemistry, ChukwuemekaOdumegwuOjukwu University Uli Anambra State
  • Nwadike Constance 1Department of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Imo State
  • Edward Ukamaka Department of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Imo State
  • Okorie Hope 1Department of Medical Laboratory Science, Faculty of Health Science, Imo State University Owerri, Imo State
  • Obi Patrick Federal Medical CentreOwerri Imo State
Keywords: Membrane depolarization, stroke, membrane potential


Aim: This study was investigated to evaluate the level of membrane potential in stroke patients in Owerri.

Material and method:   60 stroke patients and 60 apparently healthy subjects between the ages of 60 to 80years admitted to General Hospital Owerri were selected in this study. Fasting veinous blood was collected and was used for the determination of membrane potential .

Results: The results obtained revealed that the level of membrane potential was significantly decreased in stroke patients when compared with the control at P<0.05.

Conclusion: This could probably imply depolarization of cell membrane potential leading to              reduced cell activity.


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How to Cite
Johnkennedy N, Emmanuel N, Constance N, Ukamaka E, Hope O, Patrick O. Membrane depolarization in stroke patients. AMS [Internet]. 10May2017 [cited 22Feb.2020];3(4):09-1. Available from:
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