Synthesis, characterization and biological evaluation of sulfonamide based transition metal complexes

  • Hitesh R. Patel Department of Chemistry, M N Patel Science College, Vishnagar - 384315
  • Asha D. Patel Department of Chemistry, M N Patel Science College, Vishnagar - 384315
Keywords: Maleic anhydride, Sulphanilamide, Magnetic moment, Spectroscopic study and Antifungal properties

Abstract

In the present study a noval 4-oxo-4-(4-sulfamoylphenylamino)but-2-enoic acid (OSPAB) was prepared by reaction of maleic anhydride with sulphanilamide. The prepared ligand was characterized by elemental analysis and spectral studies. The transition metal complexes viz. Cu2+, Ni2+ , Co2+ , Mn2+ and  Zn2+  of OSPAB were prepared and characterized by metal-ligand (M:L) ratio, IR, reflectance spectroscopies and magnetic properties. All the prepared metal complexes and ligand were studies as antimicrobial agent. Among all the metal complexes, Zn2+ and Cu2+ metal complexes have shown significant activity.  

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Published
2015-08-07
How to Cite
1.
Patel H, Patel A. Synthesis, characterization and biological evaluation of sulfonamide based transition metal complexes. AMS [Internet]. 7Aug.2015 [cited 22Feb.2020];2(6):93-5. Available from: http://asdpub.com/index.php/ams/article/view/211
Section
Original Articles

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