The lack of sensitivity of methicillin resistant Staphylococcus aureus (MRSA) toward teicoplanin

  • Venus Hassan Abdul Amir College of Biotechnology, Al-Qasim Green University
  • Nktel Faaz Al-saad College of Biotechnology, Al-Qasim Green University
Keywords: methicillin, Staphylococcus aureus, teicoplanin

Abstract

A total of 60 methicillin resistant Staphylococcus aureus (MRSA) strains clinical samples in children were collected from cellulitis, abscess, and wound samples in Al-Hilla, and Babylon teaching hospital was identified to species level and antibiotic susceptibility testing with a VITEK-2 system. In the present study, 24 (40%) of MRSA isolates were community- acquired methicillin resistant Staphylococcus aureus (CA-MRSA), and 36 (60%) were hospitalized-acquired methicillin resistant Staphylococcus aureus (HA-MRSA). The results showed that 35 of female, and 25 of male of MRSA isolates, and these isolates were taken from 7 of infants aged less than 6 months, and 53 children aged between 6 months and 4 years of MRSA isolates. In the present study, antimicrobial susceptibility testing with the VITEK 2 system gave resistant to 10 and sensitive to 6 antibiotics to all bacterial isolates, but only 3(5%) of bacterial isolates were resistant to teicoplanin.

Downloads

Download data is not yet available.

References

- Moran, G.J.; Krishnadasan, A.; Gorwitz, R.J.; Fosheim, G.E.; McDougal, L.K.; Carey, R.B. and Talan D.A. (2006). Methicillin-resistant S. aureus infections among patients in the emergency department. N. Engl. J. Med. 355: 666-74.

- Anderson, M.E.; Lefebvre, S.L.; Rankin, S.C.; Aceto, H.; Morley, P.S.; Caron, J.P.; Welsh, R.D.; Holbrook, T.C.; Moore, B.; Taylor, D.R. and Weese J.S. (2009). Retrospective multicentre study of methicillin resistant Staphylococcus aureus infections in115 horses. Equine Vet. J. 41(4):401-5.

- Aspiroz, C.; Lozano, C.; Vindel, A.; Lasarte, J.J.; Zarazaga, M. and Torres C. (2010). Skin lesion caused by ST398 and ST1 MRSA, Spain. Emerg. Infect. Dis. 16(1):157-9.

- Bagcigil, F.A.; Moodley, A.; Baptiste, K.E.; Jensen, V.F. and Guardabassi L. (2007). Occurrence, species distribution, antimicrobial resistance and clonality of methicillin- and erythromycin-resistant staphylococci in the nasal cavity of domestic animals. Vet. Microbiol. 121(3-4):307-15.

- Weese, J.S.; Rousseau, J.; Willey, B.M.; Archambault, M.; McGeer, A. and Low D.E. (2006). MRSA in horses at a veterinary teaching hospital: frequency, characterization, and association with clinical disease. J. Vet. Intern. Med. 20 (1):182-6.

- Blaine, K.P.; Tuohy, M.J.; Wilson, D.; Procop, G.W.; Tisch, D.J.; Shrestha, N.K. and Hall G.S. (2010). Progression to bacteremia in critical care patients colonized with methicillin-resistant S. aureus expressing Panton-Valentine leukocidin. Diagn. Microbiol. Infect. Dis. 68 (1) : 28-33.

- Redpath, M.B.; Foster, T.J. and Bailey C.J. (1991). The role of serine protease active site in the mode of action of epidermolytic toxin of S. aureus. FEMS Microbiol. Lett. 81:151±6.

- Iyer, S. and Jones D. H. (2003). Community-acquired methicillin-resistant S. aureus skin infection: A retrospective analysis of clinical presentation and treatment of a local outbreak. J. of the American Academy of Dermatology. 50 (6): 854–858.

- Melish M.E. (1982). Staphylococci, streptococci and the skin: review of impetigo and staphylococcal scalded skin syndrome. Semin. Dermatol. 1:101±9.

- Kaplan, S. L.; Hulten, K. G.; Gonzalez, B. E.; Hammerman, W. A.; Lamberth, L.; Versalovic, J. and Mason E. O. (2005). Three-Year Surveillance of Community-Acquired S. aureus Infections in Children. Clin. Infect. Dis. 40 (12): 1785-1791.

- Ang, J.Y.; Ezike, E. and Asmar B. (2004). Antibacterial resistance. Indian. J. pediatr. 71 (3): 229-239.

- Weigelt J.A. (2007). MRSA Informa Healthcare. The role of nasal carriage in Staphylococcus aureus infections. Lancet. Infect. Dis. 5: 751-762.

- Forbes, B.A.; Daniel, F.S. and Alice S.W. (2007). Bailey and Scott diagnostic microbiology. 12th ed., Mosby Elsevier company, USA.

- Lindqvist, M.; Isaksson, B.; Samuelsson, A.; Nilsson, LE. and Hallgren A. (2009). A clonal outbreak of methicillin-susceptible Staphylococcus aureus with concomitant resistance to erythromycin, clindamycin and tobramycin in a Swedish county. Scand J. Infect. Dis., 41 (5): 324-33.

- Mitscher L.A .(2004). Bacterial topoisomerase inhibitors: Quinolone and pyridone antibacterial agents. Chem. Rev., 105 (2): 559-592.

- Rubin, B.K. and Tamaoki J. (2005). Antibiotics as anti-inflammatory and immunomodulatory agents. Birkhauser Verlag, PP:6.

- Lim, HS.; Lee, H.; Roh, KH.; Yum, JH.; Yong, D.; Lee, K. and Chong Y. (2006). Prevalence of inducible clindamycin resistance in staphylococcal isolates at Korean tertiary care hospital. Yonsei J. Med., 47: 480–4.

- Ge, M.; Chen, Z.; Onishi, H. R.; Kohler J.; Silver, L. L.; Kerns, R. S. Fukuzawa,Thompson, C. and Kahne D. (1999). Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding d-Ala-d-Ala. Science, 284: 507-511.

- Brooks, G.F.; Carroll, K.C.; Butel, J.S. and Morse S.A. (2007). Jawetz, melnik and aldelbergs medical microbiology. 24 rd ed. Lange Medical Books, McGraw-Hill.

- Fluit1, A. C.; Wielders, C. L. C.; Verhoef1, J. and Schmitz F.-J. (2001). Epidemiology and Susceptibility of 3,051 S.aureus Isolates from 25 University Hospitals Participating in the European SENTRY Study. J. Clin. Microbiol., 39 (10): 3727- 32.

- Drew, RH. (2007). Emerging options for treatment of invasive, multidrug-resistant Staphylococcus aureus infections. Pharmacotherapy, 27: 227-49.

- Chen, AE.; Goldstein, M.; Carroll, K.; Song, X.; Perl, TM. and Siberry GK. (2006). Evolving epidemiology of pediatric Staphylococcus aureus cutaneous infections in a Baltimore hospital. Pediatr. Emerg. Care. , 22: 717-23.

- Randrianirina, F.; Soares, JL.; Ratsima, E.; Carod, J.-F.; Combe, P.; Grosjean, P.; Richard, V. and Talarmin A. (2007). In vitro activities of 18 antimicrobial agents against Staphylococcus aureus isolates from the Institut Pasteur of Madagascar. Ann. Clin. Microbiol. Antimicrob., 6:5.

Published
2015-05-30
How to Cite
1.
Amir VH, Al-saad N. The lack of sensitivity of methicillin resistant Staphylococcus aureus (MRSA) toward teicoplanin. AMS [Internet]. 30May2015 [cited 14Nov.2024];2(1):30-2. Available from: https://asdpub.com/index.php/ams/article/view/134
Section
Original Articles

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.