The Landau Kleffner Syndrome

  • Shamama Bano M. Pharm Research Scholar, Pharmacology Department, N.I.E.T. Greater Noida, Uttar Pradesh,
  • Saumya Das Department of Pharmaceutical Technology, Noida Institute of Engineering and Technology, Greater Noida, Uttar Pradesh
  • Avijit Mazumder Department of Pharmaceutical Technology, Noida Institute of Engineering and Technology, Greater Noida, Uttar Pradesh
  • Sanjita Das Department of Pharmaceutical Technology, Noida Institute of Engineering and Technology, Greater Noida, Uttar Pradesh
  • Shaneza Aman Department of Pharmaceutical Technology, Noida Institute of Engineering and Technology, Greater Noida, Uttar Pradesh
Keywords: Landau kleffner syndrome, Aphasia, Speech delay

Abstract

The Landau Kleffner   syndrome (LKS) or the syndrome of acquired epileptic aphasia was first described in 1957. LKS also called infantile acquired aphasia, acquired epileptic aphasia or aphasia with convulsive disorder. It is a rare childhood neurological syndrome. LKS is an epilepsy syndrome involving progressive neuropsychological impairment related to the appearance of paroxysmal electroencephalograph (EEG) activity. The disorder is characterized by gradual or rapid loss of language in a previously normal child. Affected children who have developed age-appropriate speech then experience language regression with verbal auditory agnosia, abnormal epileptiform activity, behavioural disturbances, and sometimes overt seizures. Behavioral disorders such as hyperactivity, aggressiveness and depression can also accompany this disorder.

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Published
2015-06-30
Section
Review Articles