Clinical, Economic and Healthcare Constraints and Challenges Using Insulin Analogues in the Treatment and Control of Diabetes in Vulnerable Populations
Insulin constitutes the most superior, effective and consistent substance for blood glucose level control in diabetes. Insulin analogues are forms of insulin which have undergone molecular alteration. The approximate global acceptance of the transition to analogue insulins in recent decades has resulted in elevated costs, but devoid of pellucid posited evidence of the advantages in persons presenting with diabetes. Pregnancy impacts on both maternal and foetal metabolism in both diabetic and non-diabetic women; thus, insulin requirements increase at pregnancy due to progressive augmentation of insulin resistance. Universal constraints and challenges with respect to insulin access have been reported in low-income and middle-income countries as well as high-income countries in vulnerable populations and others.
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